Bone and joint pain
The blood cells are produced in the bone marrow. Leukemia causes the blood cells to replicate at an accelerated rate, resulting in extreme overcrowding and pooling of the immature and unhealthy blood cells in the bones and joints. The deposition of cells can contribute to bone and joint aches and pains. Some kids with leukemia may complain of neck or back pain, while others can develop a limp due to leg pain.
Sometimes, this back pain and limping can be the first sign of leukemia. Doctors can detect small bony spurs and overgrowths in the bones and joints – indicative of over activity in the bone marrow. This condition can be diagnosed on X-rays and CT-scans of the back and lower extremities. Supportive blood investigation such as complete blood picture and peripheral film can also aid in definitive diagnosis.