Bone pain
Achiness in the bones is a relatively rare but often overlooked and clear symptom of both acute and chronic forms of leukemia. Blood cells are produced inside the bone marrow. The bone cells start producing blood cells at an abnormal rate in leukemia. Another thing that happens is the uncontrolled and unchecked production of the blood cells. This liver functioning can cause aches and extreme pain in your bones.
Some leukemia subtypes, such as acute lymphoblastic leukemia (AML), often cause bone pain or joints in which it grows. That’s because it leaves the bone marrow overcrowded and swollen as the cancer cells take up space in the bone marrow, contributing to discomfort on or near the bones or joints.