Feeling full or bloated
The enlarged spleen is a hallmark of chronic — and sometimes acute types of leukemia. Enlargement of the spleen occurs secondary to over-functioning and production of more than required different types of blood cells. An enlarged spleen is said to put pressure on the stomach and other gut organs – which can lead to anorexia or loss of appetite. You may have what is called early satiety – a condition in which patients eat a little food but feel full because the spleen pushes up on the stomach.
Enlargement of the spleen can also be due to infections like malaria and other metabolic body conditions such as decompensated liver disease.